Biotechnology and Bioprocessing
SuperPro Designer is the leading process simulator in the biotech industry. It is used throughout the Life Cycle of Product Development and Commercialization to facilitate process optimization, cycle time reduction, improve team collaboration, and shorten the time to market. The development of SuperPro Designer was initiated at the Biotechnology Process Engineering Center (BPEC) of MIT (in the late 1980’s) and completed by INTELLIGEN (in the mid 1990’s). A partial list of users in the biotech industry follows:
Abgenix Pharmaceuticals
Ajinomoto (Japan)
Allergan
Alexion Pharmaceuticals
Amersham Biosciences
Avecia LifeScience (U.K.)
Aventis Pasteur (four sites)
Archer Daniels Midland (ADM)
Battelle Memorial Institute
Baxter
Bayer (two locations)
Biogen
BioMarin Pharmaceutical
Bio-Technical Resources
Bio-Rad Laboratories
Biochemie (Austria)
Bristol–Myers Squibb
Cangene (Canada)
Centocor
C.I.P.F. (France)
Chiron Corporation
Corixa Corporation
CRAB (Italy)
Dev. Center for Biotechn. (Taiwan)
Diosynth RTP
Diversa
Dow Chemical
Dow Corning Corp
DSM Biologics (the Netherlands)
DMV Intern. (Holland)
Ecopetrol-ICP (Columbia)
Enchira Biotechnology Corp.
Eastman Chemical Company
Enitecnologie (Italy)
Du Pont de Nemours
Genencor
Genentech
Genetics Institute
GlaxoSmithKline
Hoffman-La Roche
Human Genome Sciences
ICOS Corporation
IDEC Pharmaceuticals
Large Scale Biology
Immunex Corp.
Purdue Biopharma
Pfizer
Metabolix
Pharming
Kelco Biopolymers
Michigan Biotechnology Institute
Pharmacia Corporation
Roche Vitamins (Switzerland)
Pure World Botanicals
SAIC FREDERICK
HAUSER, Inc.
Monsanto
ProdiGene
RJ Reynolds Tobacco
Laboratoires Serono (Switzerland)
Protein Polymer Technologies
Regeneron Pharmaceuticals
Stryker Biotech
Chemland Corporation (Korea)
Eli Lilly
HECHEM (Malaysia)
Hemosol (Canada)
HENKEL CORP.
Ind. Res. Center (New Zealand)
Novo Nordisk (Denmark)
Pharmacia Biotech
Orsan-Amylum (France)
Sucromiles (Columbia)
Union Chemical Labs (Taiwan)
U.S. Department of Agriculture
US Army Edgewood CB Center
RDCAC – LIPI (Indonesia)
Samyang Genex Biotech (Korea)
QLT (Canada)
Virionyx (New Zealand)
Phytobiotech (Canada)
Wyeth-Lederle Vaccines
Maxygen
McGhan Medical Corporation
Merck & Co.
Merck KGaA (Germany)
Novo Nordisk
PLIVA d.d. ZAGREB
LONZA Biologics
IFF
SuperPro Designer is also a standard tool for Engineering & Construction (E&C) firms. It is used extensively in up-front design for sizing equipment and batch utilities. For instance, sizing of WFI stills and storage tanks is a common application of SuperPro. Another common use is for throughput analysis, debottlenecking, and cycle time reduction studies. A partial list of current users from the E&C community follows.
Arthur D. Little
Bechtel
Biometics
Brunkow Consulting
CDI / Herzog-Hart
CRB Engineers
Fluor Daniel
Jacobs Engineering
Karl Research & Consulting
Decision Management International
Gilbane
Foster Wheeler
Project Management (Ireland)
BPE Design & Support (U.K.)
Kvaerner Process (US and UK)
Lockwood Greene
Morrison Knudsen (Washington Group)
Novo Nordisk Engineering (Denmark)
Pharmaplan (Germany)
Snamprogetti Biotech (Italy)
SRI Consulting
Process Facilities Inc.
ABB Automation Inc.
Bovis Tanvec Ltd (U.K.)
3T Consult (Holland)
Philipp Hess Associates (Holland)
RINTEKNO (Finland)
Simon Carves (U.K.)
For more info on applications of SuperPro in the biotech industry, please download and have a look at some of the papers and presentation documents we have prepared on the subject.